Death-Song of Destiny! As Dr. Strange waits in a subway station, he witnesses an accident that results in a young harmonica player falling on the tracks. Instead of letting him save her, she insists that he rescue her harmonica. When she is hit by a subway train, she explodes into a shower of sparks. These sparks bath all who are present. Taking the girl's harmonica, Dr. Strange realizes that it is mystical in origin and he and Clea rush out to figure out what purpose it has.
Later, the Thing gets a call from Mrs. Coogan, whose grandson was another witness to the accident. Duffy Coogan is wracked with fear after the accident. Thing agrees to go and see her son. Meanwhile, Dr. Strange discovers that the girl was really destiny and that everyone who was exposed to the sparks is in danger. Dr. Strange then rushes out to prevent the danger posed to all.
Visiting the home of Renee and Sheldon Goldenberg, Dr. Strange saves Sheldon from becoming a faceless person. Going to the next person brings Strange into contact with Duffy Coogan and the Thing. The energy from Destiny manifests in a sewer rat which grows into giant proportions -- The personification of Duffy's fear of poverty. The Thing then teams up with Dr. Strange and they both defeat the rat, restoring it to normal.
Telling the Thing of his mission, Ben agrees to help Dr. Strange out and they both travel back to Strange's Sanctum Sanctorum, where they are told by Clea that Valkyrie had come to take the harmonica.