Doctor Stasis is a clone of Mister Sinister, one of the four created to explore different solutions to the problem of inevitable Machine supremacy in 1895. Each of the clones believed themselves to be the only one and the original Nathaniel Essex, having no memory of his death in Bedlam.
Doctor Stasis eventually traveled to America and set up a base under New York City. He used evolved animals as servants (such as the one called Bornan) whom he would repeatedly kill for their failures before bringing them back to life, and numerous fake families who he would simply kill if they disappointed him. He was also the mysterious chairman of the Oblivion Institute and eventually became director of ORCHIS's Sixth Petal.
Following the X-Men's attack on the Mother Mold, Doctor Stasis investigated the corpse of Scott Summers to try and uncover the mysteries of mutant resurrection. In order to make public perception of mutantdom more negative by pushing humanity to view Krakoa as a "secretive island cult", Stasis presented Summers' autopsy to famed Daily Bugle reporter Benjamin Urich.
